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We found no difference in terms of evolutionary rate between C domain and all other domains.
Hudson et al. (1987) established a statistical test to examine whether the DNA sequence with higher/lower evolutionary rate between species also presented higher/lower polymorphic rate within species.
Interestingly, in comparison of evolutionary rate between pika and rabbit lineages we found that the differences of the evolutionary rate between these two lineages were significant, but the differences between rabbit and all other lineages were not significant.
The equality of evolutionary rate between all sequences was tested using Tajima' relative rate test [70] in MEGA4.
Divergence-based ascertainment bias calls into question the validity of earlier studies of the site frequency spectrum from regions which have been selected based on their evolutionary rate between species but have ignored this source of error.
To compare evolutionary rate between type I and type II MADS factors in animals, substitution rates (see Figure 2) of SRF and MEF2A-D were calculated in humans and mice by using dogs and cows as outgroups.
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The uncorrelated variable rate model they use, which assumes independence of evolutionary rates between branches, may also be able to identify instantaneous accelerations.
Conversely, differences in evolutionary rates between teleost MyoD1 orthologues were not significantly different except in one case when tiger pufferfish and zebrafish MyoD1 were compared (Table S1).
Due to the lack of fossil calibration and the asymmetric evolutionary rates between subfamilies, it is difficult to estimate the precise divergence time of each node in such a long evolutionary time.
If the evolutionary rates between the original (λ1) and duplicate (λ2) stay the same or change proportionally over time, the coefficient of rate correlation (rλ) between them will be 1.
While, some AMPs are highly conserved across taxa and do not show elevated evolutionary rates between populations, a number of studies on AMP evolution within social insects showed that elevated rates of molecular evolution are possible [7].
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