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This implies that the estimated evolutionary parameters of the LFs work generally well.
We calculated the nonsynonymous and synonymous substitution rates between human and mouse from γ-MYN method [30] using KaKs_Calculator2.0 [31] as evolutionary parameters of the flanking coding regions of minimal introns in minimal intron-containing genes.
The covariance between brain structures and their correlates presented distinct evolutionary patterns between males and females, as evidenced by the differences in the values of the evolutionary parameters of the pgls models (Table 2).
Most notably, these are the evolutionary parameters of the model: the deleterious mutation rate λ, the fitness cost of deleterious mutations sd, and the antigenic mutation rate λantigenic.
We first determine the evolutionary conditions that favour cooperative binding under stabilising selection, in terms of the basic evolutionary parameters of the population: the strength of selection on binding sites, the rate of mutation, and the population size.
To evaluate the robustness of the estimates for evolutionary parameters of the global meta-alignments, we used bootstrapping to form 2000 alighments of the same length for reach global meta-alignment and estimated amino-acid identity, dN, dS, and ω = dN/dS.
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Thus, by measuring the crypt fission rate, we measured a fundamental evolutionary parameter of the human colon, which facilitates quantification of the age and rate of growth of neoplastic lesions.
We noted epidemiological, clinical, biological and evolutionary parameters of all the patients and divided them into two groups according to their osmolar states, the first non-hyperosmolar group with plasma osmolarity of less than 320 mOsm L, called the control group and the second hyperosmolar group, plasma osmolarity greater than or equal to 320 mOsm L. Results: 371 patients were included.
Because genes controlled by different evolutionary processes can share an identical evolutionary history (i.e., branching pattern), we investigated the effect of different evolutionary parameters on the power of the CADM test.
This approach allows designers to set the evolutionary parameters of mutation rate and generation size, in addition to parent selection, in order to steer design space exploration.
In previous work on context-dependent models for non-coding sequences, we have extensively discussed the importance of an adequate ancestral root sequence distribution to estimate the evolutionary parameters of context-dependent models [ 17].
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