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This review focuses on the epigenome and its effect on transcriptional regulation in P. falciparum, highlighting its unique, evolutionary diverse features.
Where successful antipathogen molecules have been developed, larger scale trials are needed along with evaluation against evolutionary diverse pathogens and varying environmental conditions to assess the robustness of resistance phenotypes.
For an evolutionary diverse superfamily such positions can be involved in its structure/function such as ligand-binding, provided an accurate MSA is used as an input.
The selected 768 small molecules (the latest version of the FOL library contains over 1400 compounds) were chosen from evolutionary diverse organisms and had molecular weight of less than 350 as previously described [18].
However, our results identify two groups of ecologically and evolutionary diverse genera that consistently display fundamentally different spatial and temporal distributions and sensitivities to environmental perturbations within the same geographic region.
The repertoire of LINC components is evolutionary diverse.
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As outlined in the concise introduction, pathogenic protozoans represent an evolutionary highly diverse and little understood group of disease-causing microorganisms.
Not much is known about mtRNase P in the evolutionary highly diverse "group" of protists.
& Hatfull, G.F. Evolutionary relationships among diverse bacteriophages and prophages: all the world's a phage.
Mohanraju, P. et al. Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.
Aravind, L. & Ponting, C. P. The GAF domain: an evolutionary link between diverse phototransducing proteins.
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