What is an evolutionary constraint?
Futuyma, D. J. Evolutionary constraint and ecological consequences.
Fraser, H. B. Modularity and evolutionary constraint on proteins.
Lindblad-Toh, K. et al. A high-resolution map of human evolutionary constraint using 29 mammals.
Paper: "A high-resolution map of human evolutionary constraint using 29 mammals".
Overall, our data suggest that protein expression levels evolve under stronger evolutionary constraint than mRNA levels.
Pervouchine, D. D. et al. Enhanced transcriptome maps from multiple mouse tissues reveal evolutionary constraint in gene expression.
Dr. Stedman's group said the findings "raise the intriguing possibility that the decrement in masticatory muscle size removed an evolutionary constraint on encephalization".
Johnson, D. S., Davidson, B., Brown, C. D., Smith, W. C. & Sidow, A. Noncoding regulatory sequences of Ciona exhibit strong correspondence between evolutionary constraint and functional importance.
Thus, gbM could potentially be a by-product of this molecular process, which could itself be subject to evolutionary constraint (Takuno and Gaut 2013; Bewick and Schmitz 2017).
We regard MRE as an evolutionary constraint.
