Sentence examples for evolutionary cancer from inspiring English sources

Both must be considered in any evolutionary cancer schema.

In the new study, Schiffman teamed up with Carlo Maley, an evolutionary cancer biologist at Arizona State University, Tempe, and colleagues.

"If we could alter our [hyaluronan] or stabilize it somehow, we may be able to suppress cancers," suggests Carlo Maley, an evolutionary cancer biologist at the University of California, San Francisco, who was not involved with the work.

The presented mechanistic approach is embedded in the classical framework of a multistage and evolutionary cancer model where individual somatic cancer evolution starts with one cell and proceeds with successive rounds of mutation acquisitions, clonal expansions and partial elimination of tumor subclones by various mechanisms (Beckman and Loeb, 2005a).

By co-opting resources, by reprogramming energy metabolism to support their own proliferation, through the evasion of immunological destruction, by recruiting other cellular constituents, and through the flexible backwardization of its evolutionary toolkit, cancer lineages enact preferential tumor microenvironments.

Genome-wide and gene-specific mutations can lead to evolutionary variation, cancer, and neurodegenerative and neuromuscular disease.

The importance of an evolutionary understanding cancer is not just an academic pursuit; it has great clinical utility that remains largely untapped.

Although it may eventually prove possible to identify unequivocally the positions of many evolutionary and cancer-associated breakpoints, there is no a priori reason to suppose that these breakpoints should occur in precisely the same locations.

In this article, we propose that to answer some of the fundamental questions regarding the evolutionary progression of cancers, cancer biologists should adopt the powerful techniques of experimental evolution.

The story of the evolutionary origins of cancer and cancer suppression mechanisms is mostly one of selection and constraints.

Our work adds a new layer of information for cancer evolutionary analysis: survival-relatedness. Cancer survival genes continued to emerge after Metazoa, and probably not coincidentally at Deuterostomia.