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This tree establishes for the first time the relative evolutionary ages of the major HCV genotypes.
Ohtani, H., Liu, M., Zhou, W., Liang, G. & Jones, P. A. Switching roles for DNA and histone methylation depend on evolutionary ages of human endogenous retroviruses.
Also of note is that neither analysis determined the relative evolutionary ages of the various genotypes.
Interestingly, subclusters C4a1b, C4a2a2a, C4a2b, C4a2a2, and C7a1a encompass predominantly Indian mtDNA genomes, and show evolutionary ages within time frames of 8 20.5 kya.
Evolutionary ages of ∼20 24 ky have been found for ancestors of subhaplogroups U5b and U5b2, which most probably were originated in southern and central part of Europe, because the majority of such haplotypes were revealed in Czechs, Slovaks and Poles and in the Mediterranean populations, based on a set of population data analyzed in the present study (Figure 1, Figure S2).
We also searched for nuwts of different evolutionary ages using BLASTN [ 21].
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Trindade, L. S. et al. A novel classification system for evolutionary aging theories.
Weakly conserved miRNA seed families would be expected to be younger in evolutionary age than highly conserved ones.
This suggests a low conservation of microsatellite flanking regions in this order regarding other fish orders of similar evolutionary age.
Simonti, C. N., Pavlicev, M. & Capra, J. A. Transposable element exaptation into regulatory regions is rare, influenced by evolutionary age, and subject to pleiotropic constraints.
We measured the evolutionary age of TEs, and found that younger TEs tended to have higher enrichment of chromatin marks, although the correlation was modest (Supplementary Figure 1b).
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