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However, there is recognized heterogeneity within any given tumor-type from patient to patient (inter-patient heterogeneity), and within an individual (intra-patient heterogeneity) as demonstrated by molecular evolution through space (primary tumor to metastasis) and time (after therapy).
It is evolution through space not time and does not depend upon differential fitness.
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Her work chronicles the evolution of the space from village green to athletic oasis.
Specifically, according to Lemey and collaborators, the state of each sequence was represented by its geographical origin and the analyses lead to infer about the state of each internal node: this approach allowed to follow the viral evolution through the space of assigned states.
This paper aims to investigate this evolution of space on different scales and means that caused by contemporary information technology through cultural and environmental aspects.
But really, it's just the evolution of space and time.
Interestingly, none of the existing epidemiological models that explicitly incorporate both evolution in sequence space and selection through immunity and cross-immunity in phenotypic space appear able to explain the two different periods observed in the data.
Urbanization processes show cycles of evolution that spread in different ways through space.
The goal of the probe is to learn more about the evolution of a comet as it travels through space.
In addition, to further optimize the sampling, we describe a preconditioning scheme, which permits to treat each field degree of freedom individually with regard to the evolution through the auxiliary field configuration space.
The new study examines 33 supermassive black holes with a more powerful diagnostic of galaxy evolution: the speeds at which a galaxy's stars orbit through space.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com