In addition to the sublimation process, however, impacts by asteroidal bodies may play a vital role in the evolution of the nucleus (e.g., Fern'andez, 1981).
The spacecraft will perform many flybys that will allow the onboard instruments to measure the evolution of the nucleus and coma with respect to the comet's initial state, defined by the data presented here.
We propose that the evolution of the nucleus was a requirement to significantly enhance the kinetics of homologous chromosome pairing.
While the evolution of all Hsp70 family members is not yet completely understood, the pathways for the evolution of the nucleus-encoded Hsp70s of the cell organelles are well known.
We agree that a heuristic understanding of the evolution of the nucleus is a point to be debated and we acknowledge this idea in the new version of the manuscript.
Because nuclear and chromatin structures are largely conserved between "lower" and "higher" eukaryotes, this argues that the evolution of p300/CBP was not triggered by the evolution of the nucleus and chromatin, but later when metazoa evolved.
Furthermore, the suggestion that chromatin compaction, presumably needed to increase resistance to ROS and UV, was the driving force behind the evolution of the nucleus, is weak, in my opinion.
Thus, it may be postulated that early in the evolution of the nucleus, the few copies of rDNA in the genome were not contained within any subnuclear structure; however, as genomes became more complex and cellular demand for protein synthesis increased, it became favorable to densely cluster a large number of rDNA repeats.
My point is not that eukaryotes have a high mutation rate today (they do not) but that they almost certainly did have one during early eukaryogenesis, especially transpositions and rearrangements; and that the evolution of the nucleus and the cell cycle restored some sort of equanimity.
This heavy intron bombardment has been argued, compellingly, to have driven the evolution of the nucleus as a way of separating the slow splicing of intronal RNA after transcription from the somewhat faster process of ribosomal translation, thereby avoiding the synthesis of aberrant proteins [ 127].
