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The dynamical rule describing the time evolution of the interacting genes is given in eq. 1. Starting from a random initial condition, we iterate the dynamics (eq. 1) to determine the activity vector as a function of time.
To investigate the relative rates of evolution among the interacting host and virus genes we next calculated the correlation between the strength of positive selection acting on the host factors and the rate of evolution of the interacting viral genes.
Although partial differential equations are available to describe the spatial and temporal evolution of the interacting system given particular initial conditions, a general overview of the phase behavior of the systems in parameter space has not yet been reported.
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The identification of particular salt bridges involved in the interaction allowed us to identify the residues of Apaf-1 that might be involved in binding of cytochrome c and to investigate the co-evolution of the interacting residues in cytochrome c and Apaf-1.
This estimator uses the explicit model of the subsystems to estimate the evolution of the states of interacting subsystems, when information about their actual values is not available.
In a containment Design Basis Accident (DBA) all these components are involved in the evolution of the accident and interact between each other.
Protein physicochemical properties must undergo complex changes during evolution, as a response to modifications in the organism environment, the result of the proteins taking up new roles or because of the need to cope with the evolution of molecular interacting partners.
Of course the success of newly introduced agricultural varieties will depend on both the local environment and the subsequent evolution of other interacting species.
This less crucial role in the PPI and high specificity for the interacting pathogens might be key factors allowing for the accelerated evolution of the membrane and envelope-interacting genes.
We apply the label 'indirect evolutionary rescue' because adaptive evolution of an interacting species (in our example, the prey) rescues a focal species (the predator) from extinction.
These contributions dominate the evolution of hot spots interacting with the local electric field over dielectric surfaces and are a key ingredient of predictive ignition models.
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