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Physicians' decisions would be strengthened if they could get help from results of accurate biomarkers reflecting the diagnosis or evolution of the infectious processes.
(ii) On the one hand, if the control law (3.15) is used instead of that in (3.7), then the time evolution of the infectious population is also given by (3.17) while the control action is active.
In the same study, the incidence increased to 60% after 2 and 3 days [25], probably because of the restoration of a normal LV afterload by norepinephrine or by the natural evolution of the infectious process.
The switched off time instant for the vaccination control action is t f ≈ 30 days as it is observed from Figures 4, 5 and 6. Figure 4 Time evolution of the infectious population and its estimate.
The evolution of the infectious process appeared to be controlled without fever after 24h of treatment and the procalcitonin level decreased.
In the same study, the incidence increased to 60% after 2 and 3 days [ 25], probably because of the restoration of a normal LV afterload by norepinephrine or by the natural evolution of the infectious process.
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There is abundant amount of research into SIR models since they capture the basic evolution mechanism of the infectious diseases when the recovered individuals will acquire life-long immunity.
Figure 3 Time evolution of the normalized infectious population for different probabilities of removing from infection.
Figure 1 Time evolution of the normalized infectious population for different infection probability.
An example based on an infectious disease where the current infection transmission depends on the time evolution of the proportion of infectious is analysed.
The evolution of the load of infectious virus, viral antigen, and viral RNA was followed for 10 days.
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