The concept of 'horizontal genomics' involves an internal contradiction because the notion of horizontal gene transfer (HGT) inherently implies the existence of a standard of vertical, tree-like evolution, and most of the existing methods for HGT detection are based on the comparison of gene trees to a standard 'species tree', in practice often the rRNA tree [ 16, 17].
In this study, we do not pretend to provide a complete update of PSP tectonic evolution but rather highlight key phases, especially during the early stages of the evolution and IBM subduction initiation, and connect them into an integrated model of evolution that satisfies the existing geological, geochemical, geochronological and mechanical constraints.
We further uncovered how network characteristics affect the evolutionary and co-evolutionary behavior of proteins and how protein evolution can modify the existing functionalities of signaling networks.
Our analysis further suggested how protein evolution could modify the existing functionalities of signaling networks.
The revised manuscript includes discussion of the existing literature on co-evolution of amino acid residues.
Evolution of a publication is not conceived as a novel publication to be created, evaluated, and published anew (with significant loss of time for the community), but rather as the evolution of an existing MSKO, possibly by different authors, with each able to claim credit and responsibility for their contribution.
This is the natural evolution of that existing benefit".
This means no group was discussing requirements regarding the evolution of an existing system.
While designing our studies, we had in mind the metaphor of a mobile app developer who would set up a group on Facebook and act as moderator; this in order to gather requirements for a new app he is planning to realize or to elicit requirements for the evolution of an existing app.
Even Google's CEO, Eric Schmidt, couldn't avoid the derivative trap: He saw the new object as a mere evolution of an existing one and shrugged off the iPad as a bigger phone.
