Sentence examples for evolution of specificity from inspiring English sources

Understanding how natural sequence variations lead to modulation of disorder is likely to be important for understanding the evolution of specificity in molecular recognition through intrinsically disordered regions (IDRs).

This allows for successful resolution in difficult cases of convergent evolution of specificity or uncertain branching in the phylogenetic tree.

This requirement for multiple epistatic mutations is likely to slow the evolution of specificity in these systems, while also significantly reducing the chance of convergent specificity evolution.

This mutual competition between restriction modification systems may have driven the evolution of specificity in the mechanisms for regulation of establishment.

These selective pressures following the process of gene duplication are key to the evolution of specificity of divergent multigene families, such as the MHPs [ 17].

In many systems, interactions between hosts and parasites involve the evolution of specificity, both within and between species (e.g. Lohse et al. 2006; Sicard et al. 2007; Poisot et al. 2011a; Koskella et al. 2012).

Thornton and collaborators have shown in detailed evolutionary, structural, and biochemical studies of the evolution of ligand specificity in glucocorticoid receptors that evolutionary transitions in ligand specificity depend on coincidental presence of certain amino acid residues, enabling the functionally adaptive amino acid substitutions.

The shared evolutionary history of CMGC kinases, combined with their diverse specificities, make them an ideal gene family for studying the evolution of kinase specificity.

The ability to invent non-promiscuous, high affinity antibodies which are 'specific' for more than one antigen such as the recently described dual-specific Two-in-One DAF antibodies, provides not only insights into the evolution of antibody specificity but also a promise of powerful medicines fully within the paradigm of targeted therapies.

Evolution of substrate specificity was reconstructed using the consensus topology based on all trees sampled from the plateau phase of the Bayesian analyses carried out with MrBayes.

In this case (Figure 5C), the evolution of host specificity in immune defense (i.e. adaptive immune system) occurs at the expense of allocation to a generalist strategy (i.e. innate immune system) [18].