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Information is sparse on the evolution of sensitivity to neutralization of HIV-1 primary isolates by antibodies that either do or don't neutralize viruses tested in cross sectional studies.
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Our results show that threshold evolution may be mediated via changes in the degree and timing of sensitivity to JH and may result in correlated changes in the dynamics and duration of larval development.
Beginning of sensitivity to light.
We suspect that the fidelity of neuronal firing in metazoans, which depend on their NaV channels, led to evolution of less sensitivity to pH and temperature, perhaps by selection of the residues that become exposed to waters within the voltage-sensing S4 and selectivity filter (Chowdhury et al., 2014).
Finally, we apply the proposed method to real data from the olfactory system of the locust and show how it can be used to analyze the temporal evolution of sensitivity.
Understanding how viruses evolve and how their evolution affects their sensitivity to different antibodies should improve our knowledge of the relationship between genetic evolution, immunity, and vaccine design.
Wilson explains that part of this evolution is our deep sensitivity to what scientists call "slip" — instant awareness of any movement of an object held in the hand.
In particular, the evolution of collateral sensitivity by adaptation to the β-lactam antibiotic could explain why inhibition usually spiked upon switches to the non- β-lactam.
To calculate the incidence of inferior alveolar nerve (IAN) damage due to lower third molar extraction and to describe the evolution of IAN sensitivity and the prognosis of IAN damage based on preoperative data.
Estimations of specific hillslope erosion, sedimentation and export rates highlight the evolution of the catchment and its sensitivity to variations in the ratio of sediment load to stream discharge.
In order to investigate the evolution of UV sensitivity in passerines and parrots, a combination of Bayesian and maximum likelihood ancestral reconstruction methods were used to infer the sequence of Helix 2 of SWS1 in the ancestors of passerines and parrots (Additional file 1: Table S4).
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