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The multiplicity of interacting partners imposes a strong functional constraint on the evolution of hub proteins (Fraser et al. 2002).
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Chinatown began in the heart of Los Angeles' downtown, however, due to the city's cultural evolution, the hub of 'real Chinese cuisine' is East of the original historic Los Angeles within the ever expanding belt loop of the San Gabriel Valley.
Finally, we established that ePPID could predict protein evolutionary rate better than the number of distinct binding interfaces for hub proteins in the Structural Interaction Network and clarified the slower evolution of co-expressed multi-interface hub proteins over that of other hub proteins.
Moreover, the application on hub proteins in the Structural Interaction Network provides further support that ePPID also gives a better prediction of protein evolutionary rate than the number of distinct binding interfaces and clarified the slower evolution of co-expressed multi-interface hub proteins over that of other hub proteins.
Unfortunately, the evolution of Boston and Silicon Valley as startup hubs reveals that it is safer to assume it will take 20 to 30 years to achieve meaningful success -- much more time than most politicians stay in office.
Although most people spend more time using their Web browser than any other program on their computers, most browsers have not kept up with the evolution of the Web into a social media hub, Mr. Andreessen said.
Yasinsky says she has observed the evolution of the film center as a creative hub among film and media studies students.
Hence, in the absence of a widely cited review, it is unclear how the presence of a paper with a high hub score influences the evolution of knowledge about the incubation period of a particular disease.
Hub location problems deal with locating a set of hub nodes and allocating non-hub nodes to the located hubs.
"People used to talk of hub fortresses.
The location of hub facilities and allocation of non-hub nodes to hubs configure the backbone of HLPs.
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