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Evolution of evidence base.
I used two examples of the evolution of evidence on the carcinogenicity of dioxins and of water DBPs.
Paralleling the evolution of evidence based medicine has been research into how evidence can be implemented into practice – so called 'implementation research' [ 8].
We explored the evolution of evidence of the effects of psychological interventions on depression and anxiety among Chinese cancer patients over time using cumulative meta-analysis [ 35].
We propose that the ideal evolution of evidence for benefit of new cancer therapies would first involve the demonstration of efficacy in a well-designed RCT powered to detect a clinically meaningful benefit.
In particular, the evolution of evidence on breast cancer and the CYP17 MspA1 variant suggests that determination of possible interactions between gene variants postulated to influence risk and nongenetic risk factors would be more efficiently accomplished by pooled analyses, ideally involving all studies of breast cancer, than by attempting to synthesize published information.
Similar(54)
The development of the LHS is a natural outcome of the evolution of evidence-based medicine (EBM).
But banks were able to step into the breach until markets recovered their nerve.The evolution of financeThe evidence of the benefits of capital markets, and in particular stockmarkets, is not just theoretical.
Rutledge and Warden (1999) originally developed the MATE to assess high school biology teachers' acceptance of evolutionary theory in terms of process of evolution, scientific validity of evolutionary theory, evolution of humans, evidence of evolution, scientific community's view of evolution, and age of the Earth.
57 The evolution of the evidence in support of prone ventilation mirrors that of high PEEP.
Hopefully, this opportunity will engender lively discussion on current topics between practitioners and also provide both within the peer-reviewed sections and without, a historical perspective on the evolution of legitimate, evidence-based interventions in aging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com