After controlling for several factors known to influence evolutionary rate, we compare the evolution of clients and nonclients under all these classifications.
Considering the high prevalence of HIV among Ethiopian FSWs [ 35] and their clients, the evolution of clients to regular, non-paying partners, and the low rate of condom use with the latter, it is likely that these partnerships present considerable risk.
But we also see some evolution of the client space, whether it's the advent of notebooks or mobile solutions or traditional clients adapted for specific uses.
Despite this experimental evidence, the extent to which chaperones facilitate the evolution of their client proteins in nature remains unclear.
The follow up of these characteristics will give insight in the evolution of the client's situation and will enable researchers to show the effect of innovation projects.
To investigate the evolution of GroEL client proteins within the Mycoplasmas, we built protein sequence alignments from the 57 genes homologous to E. coli GroEL clients using MUSCLE 3.7 (Edgar 2004) under the default parameters.
Through their modulation of the relationship between a protein's primary sequence and final structure that is, between genotype and phenotype chaperones have been proposed to facilitate the adaptive evolution of their client proteins (Rutherford and Lindquist 1998; Fares et al. 2002; Queitsch et al. 2002; Tokuriki and Tawfik 2009a, 2009b; Lindquist 2010).
The evolution of Twitter clients have been speeding along.
In the present study, our aim was to assess the effect of GroEL loss on the evolution of chaperonin clients in those Mycoplasmas that have lost GroEL.
Email has rapidly evolved since then, with the evolution of rich desktop clients, corporate email systems and webmail.
