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We can, if we wish, reduce this threat to our genetic heritage, a possession that has come down to us through some two billion years of evolution and selection of living protoplasm, and that is ours for the moment only, until we pass it on to the generation to come.
It has been proposed that TCR engagement by endogenous Sags would be one epigenetic factor that contributes to the evolution and selection of murine neoplastic T cell clones [31].
Both mutations are likely the result of virus evolution and selection of the fittest strains (20 ) during host immune responses.
In addition, identification of these subclones emerges as crucial as a concern is raised for clonal evolution and selection of resistant clones due the use of conventional (p53-dependent DNA damage) chemotherapeutic agents.
The genomic profiling of each individual cancer will potentially have a key role clinically assisting in early disease diagnosis, risk stratification, longitudinal analyses of tumor evolution and selection of the most favorable and personalized therapeutic intervention.
In this study, we sequenced mmr-b copies from 27 isolates representing 11 phylotypes of the B. plicatilis species complex, examined the mode of evolution and selection of mmr-b, and determined the relationship between mmr-b genetic distance and mate recognition among isolates.
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We do not know whether the emergence of highly efficient prion strains in nature occurs within a single life span or require evolution, adaptation, and selection of PrPSc structures.
Values of ω < 1, = 1 and > 1 indicate purifying selection, neutral evolution, and positive selection of the target gene, respectively.
Thus, epistasis may be both cryptic and pervasive, the demonstrable coevolution goes hand in hand with epistasis, and "to understand evolution and selection in proteins, knowledge of coevolution and structural change must be integrated".
Perhaps more than any other subdiscipline of biological sciences, the study of systematics tangibly and powerfully invokes the biological results of evolution and selection.
Unfortunately, we educators may perpetuate such misunderstandings, for example, if we describe only instances of evolution and selection that are progressive.
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