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There is a significant variation and a continual evolution among different groups, investigators and research sites in the development styles, design specifications and analysis protocols of newly engineered resources.
An analogous observation to such protein domain evolution among different homologues has been made on the level of gene evolution among different species[ 25].
This important disparity cautions against the extrapolation of rates of molecular evolution among different gene fragments or their combinations.
The various characteristics of SNP sites from the two miRNA families (va-miR160 and va-miR156) above suggest that significant divergence exists in miRNA conservation and evolution among different miRNA families.
Interestingly, the major gene duplication and gene loss events are found to be associated with the reproduction-related genes (such as NLRP4, 7, 8, 9, 11 and 13), implying that reproduction-related genes have undertaken a fast and diverged evolution among different mammalian lineages.
We explore and compare the adaptive rate of evolution of genes in both groups based on their function and timing or level of expression, factors that may explain variation in the rate of evolution among different genes between the different lineages.
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These results demonstrate that there is a big difference of evolution conservation among different types of J-proteins, whish in in accordance with [ 44].
Some of the important questions which may be addressed include: how do rates of sequence evolution vary among different classes of DNA; what genes or genome regions are involved in speciation, adaptation or evolution of tolerance or resistance to disease; and how much adaptive potential exists in a population after demographic decline or fragmentation?
The universal feature of the TNF pathway conserved in evolution and among different human tissues is believed to be the activation of NF-kappa-B transcription factor [17].
The change in fitness after experimental evolution varied among different evolved genotypes (F5,31 = 52.99, P < 0.0001).
Our results corroborate this hypothesis, as shown in Figure S7 of Additional file 1, as the rates of evolution vary among different tissue types.
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