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Our findings differ from prior imaging studies (using fMRI and PET CBF measures) that showed activation of limbic brain regions with exposure to cocaine-cues (scripts constructed to evoke craving or cocaine-cues videos) [30] [33].
There are abundant data, some reviewed above, showing that drug CSs can evoke craving and relapse, as well as activation of limbic cortical structures including the amygdala, OFC and ventral striatum.
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Specifically fMRI studies with exposure to either a script constructed to evoke cocaine craving or a video of cocaine-cues have shown BOLD signal increases in insular cortex as compared to a neutral script or a neutral video [27], [28].
For one thing, they are older and have been craving a kind of boutique space where bathrooms do not evoke frat houses, drinks are not served in plastic cups and fewer "little kids" crowd the room.
Craving zaatar?
Blindly craving.
Craving sporty ankle booties?
Craving some silence?
Craving an afternoon snack?
Salvador Dalí's Cravingk HaSurrealismubliSurrealism
Craving company?
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