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Moreover, in vivo combination therapy study revealed that Ce6-CuS-TSL inhibited tumor growth to a great extent without evident side effect under the laser irradiation.
The first and most evident side effect of glucosamine that patients should be aware of is shellfish allergy.
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In contrast, even using a very low-dose, paclitaxel still showed evident side effects.
In addition, apremilast effectively reduced the severity of both mAb-induced arthritis and CIA in BALB/c and DBA/1 mice, respectively, over 10 days post onset, without any evident side effects, often associated with classical PDE4 inhibitors such as rolipram.
Medication Side effects: Evident side-effects are assessed using a brief check-list considering the most common side-effects of antidepressants.
Evident side-effects are assessed using a brief version of the UKU [ 38] considering the most common side-effects of antidepressants.
Treatment was continued until disease progression became evident or side effects became intolerable.
In spite of intensive efforts intended for designing a number of different cationic lipids [ 86– 88], gene expression can only be detected after local administration instead of systemic injection, along with the evident toxic side effects of cationic lipids [ 89, 90].
Nonetheless, it seems self-evident that side effects play at least some role in lithium nonadherence.
The bikunin has many advantages such as evident effect in clinic, low side effect and low production cost.
The present results corroborate previous a study result in which tramadol, at the dose of 2 mg/kg IV, did not produce any evident intraoperative cardiorespiratory side effects and no additional analgesia was required when administered as preoperative analgesic in cats undergoing surgical gonadectomy [ 15].
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