Given the evident expression of CUL1 in the TC and EVT in first trimester placentas, we next investigated whether CUL1 has any effect on the migratory capacity of trophoblast cells.
ZR-75-1 cells, on the other hand, showed greater interactions with the E-selectin coated microtubes yielding slower cell rolling velocities of ~3 μm/s and greater numbers of interacting cells, nearly 39 cells/frame, for the 5 μg/mL concentration of E-selectin (Figs. 3a and 3b), consistent with the evident expression of sLex on the cell surface.
This result demonstrated that the immunohistochemically evident expression of IFNAR2 correlated with the expression of the active form of IFNAR2 (Yatsuhashi et al, 1999).
Activation of WNT signalling is further implied by an evident expression of β-catenin within the nucleus rather than in cytoplasm or membrane in tumour-budding cells, as well as increased laminin 5 gamma 2 and activation of SLUG and ZEB1(Muto et al, 2006; Schmalhofer et al, 2009).
In contrast, no evident expression of barhl1.1 was found in the retina at all stages analyzed, although transcripts could be clearly detected in the brain.
Hillary's cookie blunder was also striking in that — in its all too evident expression of disdain — it created a small fissure in the façade she had created over the years.
As evident by expression of the pluripotency marker SSEA1, approximately 30% of the cells at D33 remained undifferentiated (Fig. S3A, C).
During the course of tissue surveys to assess RAGE distribution in vivo, it became evident that expression of the receptor occurs in early development, especially in the central nervous system where AGEs, the presumed primary ligands for RAGE, are unlikely to be present.
Among the four human sialidases, NEU1, NEU3, and NEU4 generally show evident expression, 5 whereas the level of NEU2 is extremely low and hardly detectable.
The higher discrepancy between classifications was also evident in the expression of the CIN70 metagene in the four data sets (in Additional file 7: Figure S4).
