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L-arginine induced-acute pancreatitis was evident by increased in serum marker enzymes and by histopathological findings compared to control group.
Chronic lithium treatment significantly increased social approach, evident by increased number of nose contacts with S1 mouse, in wild-type mice (t(12) = 3.08, P = 0.01) and in Fmr1 knockout mice (t(12) = 3.33, P = 0.006).
Following UGT1A knock down, increased AR activity was evident by increased PSA expression despite no change in AR expression compared with scrambled siRNA control.
The study by Kumar et al. [ 43] reported that the ablation of miRNAs in various cancer cell lines resulted in enhanced cellular transformation, evident by increased colony formation efficiency in vitro and increased tumor burden in vivo.
As shown in Fig. 2, RWE (150 µg/mL) caused increase in cellular ROS levels as evident by increased fluorescence by ROS sensitive dihydroethidium (DHE).
Therefore impaired regeneration in aged skeletal muscle could be associated with an aging-related increase in the activation of Wnt signaling, evident by increased levels of Axin7 and β-catenin and a decrease in phosphorylated GSK3β in non-injured aged skeletal muscle cells and satellite cells and myogenic progenitor cells upon injury [ 44, 46].
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No dose response relationship was evident by increasing prescriptions of low-dose aspirin, or by tablets.
AsA-dependent antioxidant enzymes contributed to the salinity resistance as evident by increasing level of AsA and activities of Asada–Halliwell Foyer pathway enzymes (Fig. 7).
And even after the shocks stopped, their fearful expectation of a shock was evident, both by increased perspiration and on a brain-imaging MRI, whenever they saw one of the faces or smelled the odor associated with that face.
This could be due to a long presymtomatic period with increased glucose level as evident by the increased CVD risk already present with impaired glucose tolerance (IGT) [ 3, 4].
Given that increased activity of Akt has been demonstrated to play a role in endothelial cell senescence [49], it is noteworthy that the increased S6K1 in senescence/aging in our current study is associated with increased basal Akt activity as evident by the increased phosphorylation of Akt.
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