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Possible increase in hepatic GH action was also evident by increase in hepatocyte nuclear size in the iLID mice.
There was a statistically significant (P < 0.05) concentration and time dependent internalization of nanoparticles as evident by increase in the SSC intensity of treated cells.
Mechanistic studies revealed that PC induced apoptosis as evident by increase in percentage of annexin positive cells, increase in γ-H2AX levels, and by changing the Bcl-2/Bax ratio followed by release of cytochrome C and increased Caspase 9 levels.
Thus, the downregulation of the expression of Bcl-2, Bcl-xL and survivin is likely linked with lupeol's ability to induce apoptosis that is evident by increase in accumulation of lupeol-treated cells in the sub-G1 phase, processing of the initiator caspases (caspase-8 and -9), activation of the effector caspase-3 and cleavage of PARP in HCC cells.
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L-arginine induced-acute pancreatitis was evident by increased in serum marker enzymes and by histopathological findings compared to control group.
No dose response relationship was evident by increasing prescriptions of low-dose aspirin, or by tablets.
AsA-dependent antioxidant enzymes contributed to the salinity resistance as evident by increasing level of AsA and activities of Asada–Halliwell Foyer pathway enzymes (Fig. 7).
Our review indicates that in food secure population, education on CF had a significant impact on linear growth as evident by significant increase in height gain and HAZ scores, and also significantly improved weight gain, however rates of stunting reduced non-significantly.
Education in food insecure population also improved linear growth and weight gain as evident by significant increase in HAZ and WAZ scores and significant decrease in rates of stunting.
Treatment of GL261 cells at different times with TDZD-8 resulted in an increase of apoptosis that was evident by an increase in the abundance of cleaved caspase-3 (Fig. 4A).
Chronic lithium treatment significantly increased social approach, evident by increased number of nose contacts with S1 mouse, in wild-type mice (t(12) = 3.08, P = 0.01) and in Fmr1 knockout mice (t(12) = 3.33, P = 0.006).
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