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Owing to the fact that there is no evident benefit for the eradication of MRD and owing to the high costs for rituximab, the question whether all patients with newly diagnosed HCL should receive a treatment with a combination therapy including rituximab as first-line therapy cannot be answered yet.
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It was also shown that this behavioral modification of the host leads to a two-fold reduction in mortality of the parasitoid pupae with no evident benefits for the caterpillar [ 25].
Besides the evident benefits of Ca supplementation for the individual patients and their families, decreasing the number of cases of PE/E can also have significant cost saving implications for the national public health system.
The trend over the past decade of continued price escalation for devices, and the primary technology focus on cementless devices without evident incremental benefit for most patients, compounds the concern that manufacturers are excessively influencing the choice of therapies.
Work permits without an LMO are designed for international agreements, for exceptional workers who can bring evident benefits to the Canadian labour market, for international students, for the spouses or common-law partners of TFWs, or for charitable and religious work purposes.
Our civilization should be encouraged toward empathy for the evident benefits it affords our species.
Western leaders, who for years boasted about the self-evident benefits of light-touch regulation, had to sink trillions of dollars to prevent the world bank system collapsing.
"… more evident benefits were revealed in terms of error reduction.
The Portland Street project, it's already evident, has benefits for both existing residents and the new owners, on the housing ladder at last.
Concerning this proposed trial, no increased risk or toxicity seemed evident and therefore the benefit for the patients justifies conducting the trial.
External validation of the observed OS benefit for masitinib in imatinib-resistant GIST is evident in data from an independent dataset of the aforementioned phase I study [ 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com