Sentence examples for evidencing the activation of from inspiring English sources

Increased conversion of LC3-I to LC3-II, punctuated pattern of GFP-LC3 signal and transmission electron microscope observations of autophagosome structures were demonstrated after exposure of PC-3 cells to 5 mM ascorbate for 6 h, evidencing the activation of the autophagic pathway [ 52].

Through inhibition of p-mTOR via Rapamycin in PHGDH-KD ECSLCs, we were able to further enhance autophagy upregulation and promote apoptosis as evidenced by the activation of cleaved caspase-3.

Induction of apoptosis was evidenced by the activation of caspase-3 and PARP cleavage in drug-treated cells.

We show that reduction of BiP level by HKH40A impairs its function and induces unfolded protein response as evidenced by the activation of IRE1 α, ATF6 and PERK.

In particular, we find evidence that the activation of intragenic enhancers, besides affecting the activity of internal TSSs, can also potentially influence the inclusion of nearby exons.

The CEABAC mouse colonocytes showed evidence for the activation of AKT but, in preliminary experiments, no evidence for activation of the Wnt-signaling pathway could be demonstrated, in that no nuclear accumulation of β-catenin was seen (Chan and Stanners, unpublished data).

However, there is also compelling evidence that the activation of lipid biogenesis could play a more active role in cell transformation and cancer development.

Despite evidence that the activation of PPARγ may prevent cardiac fibrosis and hypertrophy, recent evidence has suggested that pharmacological activation of PPARγ causes increased cardiovascular mortality.

Nevertheless, the evidence of the activation of TrA in Pilates practitioners remains unclear.

The evidence for the activation of the allylsilane was clarified by the 31P NMR spectra.

No evidence supporting the activation of desaturase expression could be found.