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"With no good evidence for efficacy and the potential for increasing the risk for suicide, the risk-benefit balance is unfavorable," the researchers reported.
But they are the best evidence for efficacy, he believes.
Psychological treatments with scientific evidence for efficacy include relaxation training, EMG biofeedback and cognitive-behavioural therapy.
Physical therapy and acupuncture are widely used, but the scientific evidence for efficacy is sparse.
Reference: 4. Saper JR, Silberstein S. Pharmacology of dihydroergotamine and evidence for efficacy and safety in migraine.
Despite this enormous healthcare investment, mainly by direct consumer purchase, evidence for efficacy is poor by modern standards.
Despite this, the evidence for efficacy of treatment is limited, and until recently, guidance for clinicians on conservative rehabilitation programs has been inadequate.
What is the evidence for efficacy of dietary and/or supplemental ω-3 fatty acids in preventing age-related macular degeneration (AMD)?
Robert Spitzer, whose research continues to be cited by reparative therapists as evidence for efficacy of sexual orientation change efforts, admitted that his studies were fatally flawed.
Further evidence for efficacy and prognostic indicators.
Evidence for efficacy of gastroprotection strategies with NSAIDs is limited.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com