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In the same year, a French survey reporting 12 patients with BCP alternatively treated with FAC, 5-fluorouracil + epirubicin + cyclophosphamide (FEC), epirubicin + cyclophosphamide (EC) or doxorubicin + cyclophosphamide (AC) evidenced only one case of intrauterine death at 30 weeks of gestation [ 19].
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On this evidence, only one team will head into that with trepidation.
The primary suspects in the bombing by the Real IRA have been identified, including those who assembled the car bomb in Co Monaghan and drove it into Omagh, but, because of insufficient evidence, only one has been charged.
The other intervention categories provided only limited evidence (only one study per intervention).
Level 3, limited evidence: only one RCT of high quality or multiple low quality RCTs.
Level 4, no evidence: only one low quality RCT, negative or contradictory outcomes of the studies, or no relevant studies.
Second, our test allows one to detect different selective regimes, whereas classical tests are often designed to evidence only one type of selection, usually positive selection.
However, as the aim was not to perform a meta-analysis and a thorough rating of the evidence, only one researcher did the searching and primary assessments.
For the criterion of selecting the evidence only one guideline scored 4, while all the others scored 1. Developers of most guidelines had not rigorously evaluated evidence by themselves.
However, we rated the quality of this evidence as very low, due to very serious concerns about study limitations and not having enough evidence (only one study with outcome data from 50 participants).
Despite this mass of evidence, only one-quarter of Russians believe the Russia has troops in Ukraine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com