A recent research showed significantly higher concentrations of hypocretin-1 in patients with medication overuse headache and in patients with chronic migraine, evidencing a significant correlation with monthly drug intake [37].
Against this view is the finding that these perirhinal correlations did not differ significantly between the surgical and sham groups, and nor did the hippocampal fields show evidence of a significant correlation with object discrimination in the two control groups.
More recent studies provided an evidence for a significant correlation between fitness and attention [29, 30], indicating that attentional properties can be influenced by aerobic fitness training in healthy subjects [31, 32].
However, the relationship between pH and age was previously explored, but there was no evidence of a significant correlation [24], [27].
Elwood et al. did not find evidence of a significant correlation between hemoglobin concentration and four tests of memory in a subsample of 164 selected and unspecified elderly individuals, very few of whom (10%?) must have been anemic [37].
However, even if we remove these three groups there is still evidence of a significant correlation between ψ1 and θs2 for the remaining groups if we combine probabilities (p<0.0001); we can even remove Echinoderms and Molluscs, which are marginally significant individually, and the combined probability value is still significant for the remaining groups (p = 0.003).
Results obtained by performing a Spearman's correlation test on analytes identified by the previous approach (see Figure S5, Supporting Information), particularly in view of the large sample sizes used, do not provide strong evidence of a significant correlation of the protein values with the severity scale, further suggesting that the signal identified are likely to be trait markers.
However, there is evidence of a significant correlation between Ki67 and HER2 expression [ 35, 36].
