The underlying principle guiding their development realizes a tradeoff between a specificity of information granule (which we want to keep as high as possible) and the associated experimental evidence (which needs to be maintained high as well).
This dichotomy of interpretation of the evidence, which needs to be addressed globally, may result from the extremely sharp gradients in physio-chemical conditions that may occur in anchialine habitats [24].
For other areas, there was an absence of evidence which needs to be addressed.
The GBA emphasizes the quality of evidence which needs to clearly demonstrate any claimed benefit [ 48].
Similarly, often, it will be necessary to consider cost-effectiveness of an intervention, which adds a further dimension of evidence which needs considering.
This limited experimental evidence, which needs to be substantiated, suggests that DNA uptake may not involve direct pilus binding to DNA.
Clear evidence of shortcomings which need to be urgently addressed has emerged from the research.
Recommendations for universalisation of health coverage (10) increased investments in health in the 12th Five-Year Plan period (11), and the proposal for a comprehensive and convergent National Health Mission (11) is all desirable goals, which need evidence generation for their effective implementation.
This research responds to a call for more studies to focus on the under-represented 'social' component of the biopsychosocial model currently applied to our understanding of CMP [ 42], further contributing to the emerging evidence which stresses the need to acknowledge the individual's social context to improve clinical and work outcomes [ 43– 43].
A World Health Organization report based on recent research findings states that suicide is associated with a wide range of factors including mental illness, social isolation, substance abuse, and violence, but there are limited evidences for prevention approaches which need to address different risk factors at various risk levels [ 6].
