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We had previously shown that this tissue-specific peptide (70 amino acids) was required for recognition and rescue from proteasome degradation of sarcomeric substrates [18], but except for this experimental evidence, the function of this long C-terminus remained unassigned.
Based on the above evidence, the function of GGCT related to cancer cell proliferation was suggested.
Four main themes were identified in the analysis of the data: the role of evidence, the function of inter-organisational partnerships, the influence of human-based resources, and the impact of contextual factors.
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The low percentage of regulator-target pairs that have co-citations probably reflects the current relative paucity of evidence for the function of genes, with only a small percentage of genes having direct experimental evidence for their function ([ 19]).
The data also provide evidence that the function of microvascular eNOS is subject to regulation by phosphorylation.
The second was verification of the phenotype: there had to be evidence that the function of the gene affected the phenotype of the rice plant.
Evidence suggests the function of the CAR may be related to arousal, energy boost and/or anticipation, although its precise function is still unknown.
There is also evidence that the function of Twist can be modulated by phosphorylation [11], [12].
In this study we present evidence for the function of multiple relatively uncharacterized Prdm gene family members during mammalian neurogenesis.
We have extensive lines of evidence demonstrating the function of Cdk2ap1 in cell cycle regulation, apoptosis, and also growth arrest and tumor regression [5], [8], [9], [10], [34].
The data reported here provide evidence that the function of the tegument extends from its well characterized role in nutrient uptake to include waste metabolite excretion.
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