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MTC models can be fitted for all underlying evidence structures as long as the network diagram is connected.
A Bayesian approach to indirect comparison allows the inclusion of a wide range of evidence and is flexible to deal with increasingly complex evidence structures [ 2].
The selection of a gene model highlights boundaries of all overlapping evidence structures, thereby facilitating detection of alternative exon intron junctions.
We acknowledge that before widespread adoption of the framework can take place careful development of case studies is desirable to consider specific implications in more detail (e.g. such as the role of confirmatory trials) and further refine the methods, especially when using evidence structures other than standard meta-analysis to inform future research.
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A network diagram represents the underlying evidence structure of such models.
Further research will be necessary though to establish the benefits of IPD in various settings, as well as the properties of the IPD-NMA models in networks of interventions with complex evidence structure.
"We begin by stating simply that there is no evidence for structures such as neurons, synapses or a brain in plants," the authors wrote.
There is no evidence of structures inside the fort's perimeter.
Next they saw departures in temperature from the average background in the four poles of the sky – the first evidence of structure in the early universe.
Here, we present evidence that structure of the downstream region is important for replication initiation.
Analyzing implies the distinction, classification, and integration of assumptions, hypothesis, evidence, or structure of a statement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com