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Population, intervention, comparison, and outcomes (PICO) questions were reviewed and updated as needed, and evidence profiles were generated.
To determine the effects of formatting alternatives in Grading of Recommendations Assessment, Development, and Evaluation (GRADE) evidence profiles on guideline panelists' preferences, comprehension, and accessibility.
The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group has developed GRADE evidence profiles (EP) and summary of findings (SoF) tables to present evidence summaries in systematic reviews, clinical guidelines, and health technology assessments.
(PDF 314 kb) Additional file 3: GRADE evidence profiles.
Twelve evidence profiles were used in this pilot study.
We concluded that there is a need for detailed additional information in evidence profiles, and have modified the evidence profiles accordingly.
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In Table 5, the GRADE evidence profile is provided.
For each example we prepared an evidence profile.
Review Manager 5.2.5 was utilized for statistical analysis, GRADEprofiler 3.6 for evidence profile making.
A GRADE evidence profile consists of two tables: a quality assessment and a summary of findings.
Each evidence profile was made based on information available in a systematic review.
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