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However, given the evidence of persistent disease in mice expressing a non-farnesylated version of progerin, FTIs may not represent a "panacea" for this disease [37] [37].
Whereas treatment for the non-adherent patient is relatively straight-forward, difficulty arises when faced with the NRCD patient who has evidence of persistent disease but no identifiable source of continued gluten ingestion.
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The detection of hTERT expression was significantly associated with the presence of persistent disease (P =.035).
It is important, therefore, to be able to precisely localize sites of persistent disease.
In addition, Whitney et al (1999) reported that 7 of 30 (23.3%) stage IB patients with residual disease showed recurrence, whereas only 1 of 50 patients (2%) showed recurrence in the absence of evidence of persistent residual disease.
Submicroscopic evidence of persistent minimal residual disease (MRD) in first remission bone marrow samples from children with acute lymphoblastic leukaemia (ALL) indicates a high risk of clinical relapse.
Gastroenteroscopic biopsy analysis revealed no evidence of persistent Whipple's disease.
Irradiation produces tissue changes on post-treatment imaging studies, not to be misinterpreted as evidence of persistent or recurrent disease.
Patients who died with evidence of persistent or recurrent disease – MDS or lymphoid malignancy – were considered to have died from MDS/lymphoid malignancy, regardless of the immediate cause of death.
Thus it is possible that some women with evidence of persistent abnormal cytology/histology harbored disease due to other HPV types following the regression of their HPV 16/18 positive CIN 1 lesions, which may render the reported estimates of disease regression somewhat conservative.
At a median follow-up time of 9 (0.8 12) years, 19 of the 23 patients showed no evidence of recurrence or persistent disease.
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CEO of Professional Science Editing for Scientists @ prosciediting.com