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Sensitivity analyses were also conducted assuming lower discontinuation rates, as the Cochrane reviews present evidence of modified dose-escalation regimens for each of the three therapies leading to significantly fewer drop-outs over the trial periods.
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Conclusions Both BDNF and 5-HTTLPR genes show evidence of modifying the risk of a subsequent new depressive episode associated with elevated morning salivary cortisol.
In the stratified analysis performed to identify the sources of heterogeneity, only the different level of control for possible confounders showed evidence of modifying the summary analysis of Myeloma (P-value 0.0002).
The model's covariates were week of injection, lot number, and interaction between week and lot variables, selected because these variables showed evidence of modifying results.
The goal of these studies was to provide validity and reliability evidence of a modified Positive and Negative Affect Schedule (PANAS) including a direction scale (PANAS-D).
We, however, find no evidence of a modified 5′ cap in Hematodinium sp., nor in dinophyceans (Jackson et al. 2007), so this appears to be a character specific to O. marina.
Serotonin-like immunoreactivity accordingly does not provide any evidence for modified ganglionic concentrations of neurons or even ganglion rudiments in Onychophora.
Experimental evidence for the involvement of modified self is found in the specificity of autoantibodies that are found in SLE patients.
There is some evidence of BMI modifying posture and movement of the lumbar spine [ 18], and different movement strategies from sitting to standing have been reported between obese and normal individuals [ 36].
We compared the strength of the human and nonhuman evidence ratings from step 3 of the Navigation Guide (Woodruff et al. 2011a), which was based on the method used by IARC (2006), and we used their descriptors of strength of evidence, modified to be relevant for noncarcinogenic assessments (Woodruff and Sutton 2014).
Of interest, Xu et al. presented convincing evidence for modifying effects of genetic ARID5B variants; in particular these data consistently show a trend for increasing allelic odds ratio as age decreased and the risk varied substantially by ethnicity [ 14].
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