Of patients not in control for each risk factor, only 20 23% had evidence of poor medication adherence; from 30 to 47% were adherent to prescribed medications but had not received treatment intensification in response to elevated risk factor levels (30).
Dr Hans Geyer has been evaluating doping control forms and urine samples for a decade looking for evidence of pain medication.
Similar to the present study, Copher et al. required both a PH diagnosis and evidence of PAH medication use for study inclusion.
A small proportion of study subjects (6%) had evidence of PAH medication use prior to the index date, and this may have affected comparisons of costs between the baseline and follow-up period (as on average lower total costs were observed after PAH medication use).
HMG-CoA reductase inhibitors, fibrates, and diuretics are the agents most commonly associated with drug-induced rhabdomyolysis, and we evaluated the patients for systemic evidence of these medications [1, 16, 17].
HMG-CoA reductase inhibitors, fibrates, and diuretics are the agents most commonly associated with drug-induced rhabdomyolysis, and we evaluated the patients for systemic evidence of these medications [ 1, 16, 17].
Lastly, HDL-C values were extracted for subjects both prior to ("pre-medication HDL-C") or following ("post-medication HDL-C") evidence of lipid-lowering medications and the median value was reported.
Subjects with no evidence of lipid-lowering medication prescriptions were considered "pre-medication HDL-C".
The index date for the PAH medication group was designated as the earliest date of a medical or pharmacy claim with evidence of PAH-indicated medication in the identification period.
The index date for the final study sample was designated as the earliest date of a medical or pharmacy claim with evidence of PAH-indicated medication in the identification period.
