As in the case of GO 0006955, the sets identified in the meta-GSCA are largely those showing moderate, but not necessarily statistically significant evidence of DC within each study.
Although we found evidence of DC activation (CD11clow and MHC class IIhigh) by IL-12/15/18-preactivated NK cells, donor T-cell proliferation in vivo was actually inhibited by IL-12/15/18-preactivated donor NK cells.
As with many dispersion indices one could consider, the ones proposed in Equations (1) and (2) can achieve significance for gene sets with a few highly DC gene pairs as well as those showing moderate evidence of DC across many pairs.
The first evidence of DCs in zebrafish was reported by Ai-Fu and colleagues, who elegantly showed co-expression of DC-SIGN (also known as CD209) with other DC markers (CD80, CD83), as well as the functionality of CD209, in vaccination studies (Lin et al., 2009).
To provide a higher level of evidence for DC-SCRIPT mRNA expression as a prognostic marker, we now report on DC-SCRIPT expression and its significance in a retrospective validation study of 1,505 breast cancer patients with known ESR1, ESR2, and PGR expression levels.
Since there is increasing evidence of crosstalk between DC and NK cells [33], there is a possibility that CFA-activated APC may also activate NK cells that appear to be involved in CFA-mediated diabetes prevention [23].
We examined the hypotheses that the IVCM scarring score and inflammatory cell count would correspond to the grading of histological parameters, and that IVCM dendritiform cells (DFC) would be associated with the immunohistological evidence of dendritic cells (DC).
Trump could laugh off the scorn of people like Kirk and Armitage if he were riding a wave of populism to the White House, but there's mounting evidence that people outside of DC aren't warming to his schtick either.
This review focuses on the current evidence of the role of DC in fibrosis progression in NAFLD.
There is evidence about the role of DC in liver fibrosis, but it is not clearly understood.
The prebiotic showed no beneficial effects, and there was no difference in the faecal levels of F. prausnitzii, although some evidence of the modulation of DC function did exist.
