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Higher recall rates for different antibodies for this example could be reached with searches for a broader disease area like Lung Neoplasms (31 abstracts), the search with the Diagnostic subclass Immunohistochemistry in combination with the text search 'anti-Muc1' (105 abstracts), or in combination with the gene concept Muc1 and the Evidence marker Expression (1055 abstracts).
When compared to the MS gold standard, the combination of classes Clinical Management, Evidence Marker and Prognosis or Diagnosis performs even better than Clinical Management and Evidence Marker alone but loses some recall at lower ranks.
For recall value of 0.3, the precision is similar for all selections even with the combination of the classes Clinical Management, Evidence Marker and Prognosis.
Genes retrieved by the selection of Clinical Management and Evidence Marker classes and not mentioned in the AD gold standard were checked manually by a biologist using the SCAIView environment.
By additive selection of the Clinical Management or Evidence Marker classes, it can be shown that the relevant biomarker candidate genes are retrieved at higher ranks in both Alzheimer's and multiple sclerosis contexts.
The analysis of the retrieved abstracts for the first 10 ranked genes implies that the combination of different biomarker classes (Clinical Management and Evidence Marker alone or together with Diagnostics and Prognosis) leads to a reduction in the number of abstracts but to an increase in the number of remaining ones.
Similar(53)
They function more like forensic evidence, markers left behind by the dead, the lost or the emotionally absent as proof of their existence.
Several bullet holes pocked a cement wall, and evidence markers indicated at least 27 shell casings.
There was so much evidence, she said, that she and her colleagues ran out of evidence markers and had to use index cards to complete their evaluation of the scene.
The testimony came on a day that police officers took the witness stand to describe their jobs in the hours after the shooting: securing the scene with yellow tape and evidence markers and searching for evidence.
Late Saturday morning, much of the block was still cordoned off and at least a dozen evidence markers were on the ground where shell casings had been found.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com