Sentence examples for evidence linkage from inspiring English sources

Despite initial confusion and controversy due to the genetic heterogeneity of AD [ 6, 7], extending even to the small subset of FAD, a combination of functional evidence, linkage analyses and sequence comparisons led to the identification of the three genes accounting for most FAD cases: APP [ 8], PSEN1 [ 9] and PSEN2 [ 10].

Third, means of evidence linkages seem to currently be the most promising approaches for evaluating the clinical efficacy and safety of PURAS-aided risk assessment.

Linkage disequilibrium (LD) among markers can induce false-positive evidence of linkage in multipoint linkage analyses.

Based on evidence of linkage, a comprehensive linkage map was developed around this region [ 14].

Consistent evidence of linkage across multiple methods increases support for a true linkage.

Analysis of polymorphic markers provided evidence against linkage to BRCA1, but the sibship was consistent with linkage to BRCA2.

Therefore, we examined the evidence for linkage to both these phenotypes, and found evidence for suggestive linkage at multiple locations.

The present genome scanning of three Danish family samples revealed a number of loci showing evidence of linkage to AR. Chromosome 1p13 reached genome-wide significance, whereas suggestive evidence of linkage was found on chromosome 1q, 2q, 12p, and 20p.

Furthermore, evidence of linkage in the twin cohort (whole-body BMD; LOD 2.4) at chromosome 1p36 (17 cM) supports previous findings of suggestive linkage to BMD in the region.

Finally, the transmission disequilibrium test showed evidence for linkage between B2A2 haplotype and schizophrenia.

Weaker evidence of linkage (LOD 1.0 2.3) in either cohort, but not both, indicates the locality of additional QTLs.