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Correlations between landscape metrics and land suitability parameters also provided evidence for the functionality of the cancer-treating growth pattern in terms of area and connectivity metrics.
Taken together, these results provide evidence for the functionality of glyoxylate cycle genes in B. pseudomallei and may thus be useful for designing antimicrobials targeted at the glyoxylate cycle.
We provide evidence for the functionality of transferred ncRNAs by demonstrating siRNA-mediated changes in protein levels and cellular phenotype as well as decreased twinfilin-1 (twf-1) transcript levels by its upstream miR-1 regulator.
In the present context, the use of DAPI, together with fluorescence imaging, established DNA delivery to the cell nucleus, whereas the use of pCMV/p53 western blot provided evidence for the functionality of delivered DNA.
However, other types of sequence analysis provided several lines of evidence for the functionality of PNG2 repeat regions at the protein level.
Regardless, the observation that a motif has a non-random positional distribution provides further evidence for the functionality of the computationally predicted motifs.
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There is also evidence of the functionality of AuxRE/MYB elements.
This system is both amenable to large-scale production efforts and provides the first known evidence for the in vivo functionality of hESC-derived platelets.
Comparative analysis can provide powerful evidence for the in vivo functionality of TF binding, and provides a means to eliminate false positives from the large result sets typically created by PWM-based TFBS prediction programs.
Assessment of evidence for lncRNA functionality Consider the evidence for each of the many known transcriptional or post-transcriptional, nuclear or cytoplasmic, cis or trans, RNA-dependent or -independent mechanisms of lncRNAs.
Although the simple clustering in clade V is not enough to recognize a gene as a susceptibility factor, it does provide the first evidence for functionality and allows for the reduction in the number of candidates for further functional analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com