Co-occurrence of gene names in publication abstracts, entire publications, or other gene-related databases has been used to derive co-occurrence networks with clear evidence that edges in those networks are reflecting functionally relevant relationships [8] [11].
In addition to verifying existing literature evidence supporting edges in the network models, NVC participants could add novel biological information in the form of new literature evidence (for an existing edge) or contribute new network edges to incorporate new biological components into the network structure.
Magger et al. provide some evidence that edges involving such genes are the source of prediction errors, as simply down-ranking the genes after analyzing a generic (non-tissue-specific) network was not as effective.
We provide mechanistic evidence that edge-effects can manifest as cryptic losses of crucial biotic interactions that maintain diversity.
Evidence of edge loading, whereby the femoral component articulates at the margin of the tibial bearing, was common.
Based on evidence of edge effects in terrestrial landscapes, we also tested the hypothesis that predation is elevated at ecotones separating eelgrass from adjacent barren mud substrate.
There's no evidence of edge enhancement, either.
In a previous simulation study, Webster et al. [ 28] found little evidence of edge effects interfering with estimating the true odds ratio surface using loess as the spatial smoother in a generalized additive model.
The specimens were assessed for evidence of edge polish from repeated gnawing, tooth pits or punctures perpendicular to the surface of the bone, tooth scores, striations and/or furrows (V or U-shaped in cross section), and traces of gastric corrosion (Haynes, 1983; de Ruiter and Berger, 2000; Pickering et al., 2004; Pokines and Symes, 2013; Supplementary file 2).
This is evidenced for edge dislocations in virgin nuclear graphite as well as for residues of graphene layers in highly damaged graphite.
