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This is one of the most tightly constructed movements ever composed, with 30 variations (and a concluding coda) on the melody you hear blazed out at the beginning in the brass and woodwind; that melody is part of the texture of every single succeeding variation, as the passacaglia form demands.
In 1819, a Viennese music publisher wrote a waltz and asked dozens of composers to write a single variation.
And those are just the fatalities that resulted from a single variation in one factor in one small state in one twenty-five-year period.
From this single variation it is clear that Moscheles, like Beethoven, saw the awkward yet intriguing touches in Diabelli's seemingly bumptious tune.
Because genes come in pairs (alleles), a person with potentially harmful variations in both alleles is presumably at even greater risk than someone with a single variation.
In 1819, Anton Diabelli, a Viennese music publisher, composed a little waltz and sent it to dozens of composers — he wanted each of them to write and send him a single variation, which he'd publish together in one volume.
This single variation is ancient enough to support the theory, to which I have long subscribed, that the earliest division among dogs was between large ones and small ones.
I've used a computer since 1989 and the established codes of layout have been in place since then with only a single variation in the font: Arial, double-spaced, justified.
GM (1, 1) means a single differential equation model with a single variation.
Creating this exceptional procedure was necessary because of the availability of a single variation packet having the possibility of a large variation space existing within it.
Most egregiously, say the tobacco manufacturers, a company cannot sell more than a single variation of the same brand: Marlboro Red and Marlboro Light, for example.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com