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Blocking the non-specific background due to FcRs or ionic and hydrophobic interactions is considered an obligatory step prior to incubation with primary Ab.
The Institut Montaigne study concluded that, for the most talented French economics students, studies in the United States are an "obligatory step" toward a doctorate.
Thus, downregulation of Sost/sclerostin in osteocytes is an obligatory step in the mechanotransduction cascade that activates Wnt signaling and directs osteogenesis to where bone is structurally needed.
Ultrasound probe calibration is an obligatory step to build 3-D volumes from 2-D images acquired in a freehand US system.
As the key obligatory step in the glycolytic pathway, the regulation of phosphofructokinase (PFK-1) has been the focus of study of several laboratories.
Plasmodium sporozoites are transmitted through the bite of infected mosquitoes and first invade the liver of the mammalian host, as an obligatory step of the life cycle of the malaria parasite.
A common genomic organization and molecular mechanisms of replication in hosts are shared by flaviviruses with a viral serine protease playing a pivotal role in processing the viral polyprotein into component polypeptides, an obligatory step in viral replication.
The obligatory step in sterol biosynthesis in eukaryotes is demethylation of sterol precursors at the C14-position, which is catalyzed by CYP51 (sterol 14-alpha demethylase) in three sequential reactions.
DARPP-32 activation is thus an obligatory step in progestin receptor regulation of sexual receptivity in rats and mice.
While groups like HEART are striving to make an impact via resources and workshops for Muslim youth, dismantling further ingrained mindsets regarding the role of boys and men in such scenarios remains an obligatory step to consider.
The liver stage of Plasmodium's life cycle is the first, obligatory step in malaria infection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com