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Untreated, onchocerciasis leads to progressive visual impairment and eventually irreversible blindness, as well as severe itching and a range of serious skin complaints, collectively known as onchodermatitis.
The benefits of such strategies are obvious and would permit the possible identification of those genes that contribute to the multistage process that is eventually irreversible.
By the time of isolation of the PDR microorganism the patient's condition was steadily deteriorating; eventually irreversible septic shock and multiple organ failure led to his death on the 68th day of ICU stay.
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As for monomer attachment to the membrane, it will eventually become irreversible because of the irreversibility of the subsequent oligomerization.
These observations are consistent with short-term, particle surface charge controls on bacteria transport, where a negatively charged surface induced by silver nanoparticles reverses the positive charge due to iron oxide coatings, but columns eventually recovered irreversible cell deposition.
Persistent synovitis leads to massive joint destruction, and eventually causes irreversible disability in patients.
Bleeding, leaking, and scarring from these blood vessels eventually cause irreversible damage to the photoreceptors and rapid vision loss if left untreated.
In both animal and human studies, all subjects above the threshold dose eventually suffer irreversible pulmonary damage and death (Morgan and Breit, 1995).
Rheumatoid arthritis (RA) is a chronic autoimmune disease, which affects the synovial membrane and eventually causes irreversible destruction of tendons, cartilage, and bone [ 1- 3].
The simulation study here pictures a possible pathway for the genetic takeover, seeded by the emergence of a moderate Nrr, getting spread via the environmental change favoring DNA, and eventually becoming irreversible accompanying the enlargement of the genome.
In addition, P450s have a tendency to eventually undergo irreversible inactivation that can be promoted by reduced coupling between substrate binding and conformational shifts, as well as by other poorly understood determinants of catalytic stability [ 19, 42, 43].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com