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Recruitment of SURF leads to a decrease in translation and eventually degradation of the transcript (Isken et al, 2008).
After approaching the lysosomes, autophagosome-lysosome fusion occurs to form autolysosomes. Eventually, degradation takes place through the mediation of lysosomal hydrolase enzymes [ 99].
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Additionally, cytosolic nucleases will eventually degrade cytosolic DNA or RNA, so effective translocation must occur prior to degradation.
The release profile of the drug can actually be tuned by the complex interplay of several release mechanisms, including the permeability and eventually the degradation rate of the microcarriers and the diffusion through the hydrogel.
A commons pasture is used by many herders, and the best strategy for an individual herder is to add as many cattle as possible, even if this eventually causes degradation of the pasture.
The matrix eventually undergoes degradation, while simultaneously the host's cells invade and proliferate within it.
Mutations in the DES gene result in formation of inclusion bodies, weakening of the desmin cytoskeleton, disruption of subcellular organelle organization, and, eventually, myofibril degradation.
RA is an autoimmune disorder in which unchecked immune and inflammatory responses cause articular pain and eventually cartilage degradation and bone destruction [ 11].
Fruit development and ripening consist of complex biological processes associated with major metabolic pathways and cellular processes undergoing gradual switches from cell division to energy, nutrient and metabolite storage during cell expansion and eventually starch degradation during ripening.
Narendra et al. have further shown that full length PINK1 accumulates on these dysfunctional mitochondria, leading to the recruitment of parkin at the outer membrane of these damaged mitochondria and eventually their degradation by mitophagy (Fig. 2) [120].
Such a cracking eventually causes severe degradation of the critical current density.
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CEO of Professional Science Editing for Scientists @ prosciediting.com