The highly timed and interrelated nature of spermatogenesis, whereby immature spermatogonia develop into mature spermatids for their eventual release and continued maturation through the epididymis, underscores their vulnerability throughout this sensitive window in relation to environmental influences.
Morphologic sperm characteristics, including those involving the tail, may provide information about underlying mechanisms during the maturation process and eventual fertility, particularly in the context of other biochemical markers (Durutovic et al. 2013).
Our results suggest that vps-15 and ippk-1 are important during adult oogenesis and may contribute to the dynamic remodeling of membranes that must accompany the movement of oocyte precursors in the syncytial hermaphrodite gonad, and their eventual cellularization and enlargement prior to maturation and fertilization.
In addition, our histologic analyses revealed a predominance of large chondrocytic cells at the sites of eventual ankylosis, suggesting that dysregulation of chondrocyte maturation underlies the development of ankylosis in ank/ank mice.
>> The DC maturation process contributes to the eventual activation of naïve T-cells along with the generation of antigen-specific memory T-cells; this pathway begins with antigenic stimulation, which occurs through DC detection and uptake of particles.
The various types of ovarian activity reported here are explained as being part of the normal sequence seen during the change from the amenorrhoea of childhood through anovulatory ovarian activity at menarche and the gradual maturation of the ovulatory mechanism to the eventual establishment of the fertile ovulatory cycle.
Chemical signals and other external factors often regulate the biofilm lifecycle in bacteria, a sequential process typified by initial attachment of planktonic cells, microcolony formation, maturation into larger structures innervated by aqueous pores or channels, and eventual breakdown or dispersal [ 5, 21, 22].
The eventual replacement of the cartilaginous anlagen by bone and marrow relies on the sequential maturation of chondrocytes to hypertrophy.
Immature DCs contain large numbers of intracellular MHC class II rich compartments; as maturation takes place, MHC peptide complexes are exported to the cell membrane for eventual antigen presentation to T-cells [ 68].
The textual transmission of Buddhism signals a process of "knowledge convection" that can easily result in energy dissipation a possibility that seems to have informed speculations about the eventual demise of the effectiveness of the Dharma that were widely prevalent during the period of Chan's emergence and maturation.
