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In other words, it doesn't include the costs of replacing train sets once they're too old to repair or the eventual maintenance that the project's many tunnels, viaducts, and miles of wiring and electronics will need.
First intended for a lower powered engine, the N-3PB was ultimately powered by a Wright Cyclone radial engine, of the same type specified for the Douglas 8A-5N bombers and Curtiss Hawk 75A-8s ordered by Norway at the same time, simplifying the eventual maintenance and operation requirements for the entire Norwegian military aircraft fleets.
This provides the possibility for multiple stable states and thus eventual maintenance of biodiversity.
Application of the new knowledge has immediate relevance for the treatment of metastatic breast cancer and the eventual maintenance of breast cancer patients for decades using cycles of antihormones, but with regular 'oestrogen purges' to kill resistant cells, and subsequently reactivate antihormonal therapy.
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It covers every stage of the project, from the initial identification of an energy-efficient building to its eventual Operation and Maintenance (O&M), focusing specifically on appropriate energy-saving strategies and technologies for existing buildings in South Korea.
Thus, it is possible to minimize the costs associated with maintenance and eventual failure while explicitly considering uncertainties in the crack propagation phenomenon and inspection activities.
This may be true by just comparing the one off economic and carbon impact of refurbishment with the one off cost of new build, but looking at the total cost of a refurbishment project over its lifetime (including maintenance and eventual replacement) in both cash and carbon terms the outcome can be very different.
One possible solution would be to decellularize xenogeneic articular cartilage in such a way that the structure of the tissue is maintained, and to then repopulate this decellularized matrix with human chondroprogenitor cells that will facilitate the reconstitution, maintenance and eventual turnover of the construct following implantation.
This in turn should facilitate the optimization of culture conditions for iPSCs maintenance, and eventual establishment of true ESCs from sheep blastocysts.
Focus may also be expanded to different time points in the life cycle, to not only the developmental emergence of cognitive function but also the stabilization, maintenance and eventual decline, having potential translational value in the treatment of neurodegenerative disease.
While forestry might in many cases seem to be a solution, the economic and social problems of this as a suitable land use alternative are considerable, not least the funding for afforestation and reforestation projects and the organizational arrangements needed to ensure the proper maintenance and eventual use of new forest and rejuvenated areas.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com