Longitudinal assessment of lung function (FEV1 and peak flow) and symptoms were undertaken, with event studies of high pollution on biomarkers of exposure (urinary 1-hydroxypyrene) and effect (exhaled breath condensate (EBC) pH and hydrogen peroxide concentration).
Cheng, J., Pullenayegum, E., Marshall, J. K., Iorio, A. & Thabane, L. Impact of including or excluding both-armed zero-event studies on using standard meta-analysis methods for rare event outcome: a simulation study.
Containing case studies on events from the 1990s through today, Public Health Preparedness explores responses to infectious disease, bioterrorism, and natural disasters.
Especially for the event studies focusing on the impact of political events or macroeconomic announcements in Turkey, there is a risk of clustering due to the application of same event date for all observations.
(Defs.' Mem. 44-46). Likewise, they dubiously suggest that the testimony of Dr. M. Laurentius Marais, a published expert regarding event study methodology, is "irrelevant" because he rebuts only one of their several attacks on Plaintiffs' event studies.
I also comment on what event studies can and cannot tell us about the effects of regulatory changes, and on ways to more effectively implement them.
See Laura Starks, Discussion of Market Microstructure: An Examination of the Effects on Intraday Event Studies, 10 Contemp.
129 (2007) (highlighting "the importance of explicitly controlling for unrelated events occurring during the estimation window" of an event study"); John D. Jackson et al., The Impact of Non-Normality and Misspecification on Merger Event Studies, 13:2 Int.
For example, Defendants criticize Dr. Marais for not opining on whether one step the event study is "replicable" based on a purported percentage of variance in implementation, however, Dr. Marais testified that no artificial percentage of variance can answer the question because the relevant issue is whether that variance translates into a different ultimate outcome for the event study as a whole.
25 While there is no evidence of a differential rate of amputations between these debridement treatments, given the substantial clinical and economic implications of this event future studies on leg ulcer should systematically collect data on amputations to be included in economic analyses.
