Speed and ambition were critical and project management has been by deadlines - external events fixed in time for which the project had to have something to show.
Note that the sequential and additive arrival at the phenotypically meaningful sequence of A plus T plus G, represents, in reality, the accumulation of events fixed by natural selection during protein evolution, which entails clustered changes of multiple parts, and at diverse locations, within functional domains.
Acute genitourinary toxicity was similar (RR 1.13, 95% CI 0.81 1.59; P = 0.47), as was the incidence of late adverse events (fixed effect for gastrointestinal toxicity, RR 1.07, 95% CI 0.59 1.95, P = 0.82; fixed effect for genitourinary toxicity, RR 1.43, 95% CI 0.47 4.34, P = 0.52).
In comparative studies of rare events, fixing group sizes may result in groups with zero events.
I realize this probably would be blazingly obvious to anyone who knows my routine: frantically trying to run all my errands, carting kids to and from birthday parties and sporting events, fixing things around the house, paying bills and squeezing in some hasty gardening, getting caught up on email and grocery shopping and school forms all while trying to "be present" for my children.
Because of the low sensitivity of this analysis to the event depth, the depth of the induced event is fixed at 8 km, which is a typical depth of earthquakes in Oita region after M7.3 event.
The Cox model assumes that the hazard of the event remains fixed through time, that is, the effect of the individual covariates remains the same and proportional.
The event that fixed human rights as a core U.S.-China issue was the violent crackdown against student demonstrators in Beijing on June 4 , 1989– the so-called Tiananmen Incident.
This isn't to say that the event was fixed, exactly.
