The timing is awkward: Mr. Bloomberg is scheduled to be sworn in on Friday at City Hall for his third term, and has shied from any display of lavish spending for the event, even dispensing with the traditional post-ceremony party.
For each visit, we will check eligibility, end points/outcome measures, safety (general and specific safety assessments, e.g. specific laboratory tests), adverse event collection, dispensing of study drugs, compliance with study drugs, recording of concomitant medications, and laboratory tests to evaluate treatment response as defined in the schedule.
In contrast to CMA1, CMA2 requires only one dispensing event to be calculated.
Measurement strategies that require a second dispensing event evidence even greater upward bias.
Comparative analysis found a relative upward bias in adherence estimates for those measures that require at least one dispensing event to be calculated.
The fact that the measurement windows for CMA1, CMA3, and CMA5 also all end with a dispensing event leads to a further upward bias, since they effectively require that one is actively using the medication throughout the measurement window (or at least at both the beginning and end of the window).
Thus two dispensing events are required to calculate the measure.
Prescription dispensing events were drawn from a U.S. national claims database including over 80managed-caremanaged-care
The CDM contains over 60 million drug dispensing events, 140 million patient diagnoses, and 360 million clinical observations (e.g., laboratory results, diagnose codes, medications).
It would also by definition be definable for all subjects, and not just those with one or more dispensing events during the observation window.
