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Phenoxide ions, generated by treating a phenol with sodium hydroxide, are so strongly activated that they undergo electrophilic aromatic substitution even with very weak electrophiles such as carbon dioxide (CO2).
Nevertheless, as Hmg1p, which showed almost no morphologic change [8] was identified as the target candidate of lovastatin, even with very weak phenotype it may be possible to identify the candidate, suggesting that strong statistical power is needed to detect target-related mutants which show weak phenotypes (e.g., vma1, vma8 and vma11).
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Previous studies showed that cetuximab had potential ADCC activity against EGFR-expressing lung cancer cell lines, even those with very weak EGFR expression levels that are faintly detectable by immunohistochemistry [33].
For phage populations with minimal genetic load, engineering mutation rate increases beyond the mutation selection balance optimum may provide even greater protection against emergent bacterial types, but only with very weak selective coefficients for de novo deleterious mutations (below ∼0.01).
"But look at what's happened with very weak rhetoric over the last 25 years.
When individualism came here, it came to a country with very weak social institutions.
The firmicute sequences are paraphyletic, albeit with very weak support.
Many important extended temporal logics become generally undecidable, even under very weak assumptions.
In 2D crowded conditions, protein molecules frequently interact with each other even under a very weak attractive force between the molecules, which sometimes results in the formation of 2D crystals.
Consequently, mobile homes even ones with anchors or tie-downs offer no sheltie-downs offerery weak tornodoeshelter
Numerous studies have shown that even very old, very weak people can gain strength and mobility through modest strength training.
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